Integrated Drug Discovery

Yashraj Biotechnology Ltd. (YBL) has recently ventured into the drug discovery and development arena with its in-house developed cross-disciplinary technology. As a partner in integrated drug discover services, YBL offers unique and specialized support that bridges the entire drug development process, With YBL’s support, you can eliminate complicated logistics, increased administrative and regulatory costs and cycle time slippage as we manage your project every step of the way. At YBL, we make every effort to reduce the time from lab to clinic when you outsource your candidate lead generation, lead optimization, safety and efficacy to our single, efficient integrated team. Our talented team of scientists and executives work closely with client counterparts in an integrated fashion to identify promising candidates using our proprietary iPSC-based 2D and 3D cell platforms along with animal models and CRISPR-editing gene technology for rapidly advancing towards the target product profile.

Target screening

Lead identification & validation
Preclinical safety & efficacy studies on human models
(in-vitro & ex-vivo)
Target Screeing Lead Identification & Validatione Chemistry Manufacturing Control (CMC) Pre-Clinical Pharmacology Screening Clinical Pharmacology
2D & 3D Models (Normal & Diseased) Drug Screening Cell Line Development on Mammalian, Microbial & Insect Human Model Safety, Efficacy & dose ranging

  • Organoids (hiPSC)
  • Spheroids (hiPSC)
  • 2D models
  • Immunoassay Development & Studies

Customized disease modelling by CRISPER gene editing

Expansion of Therapeutic Indications

  • Organoids (hiPSC)
  • Spheroids (hiPSC)
  • 2D models
High Content Imaging Platforms Peptide and Immunoconjugates

  • Antibody-Drug Conjugation
  • Peptide (Chemically Synthesized & Recombinant)
Bio Assays

  • In-Vitro assays
  • Ex-Vivo assays
  • Immunogenicity studies
  • Immunohistochemistry
  • In-situ hybridization
  • Molecular Assays
Immunogenicity assay development & studies

  • Companion Diagnostics
Functional Assays Process Development

  • Upstream
  • Downstream
  • Formulation
Xenograft Models for Cancer

  • Patient Derived Xenograft (PDX)
  • Cell Line Derived Xenograft (CDX)
Analytical Development

  • Physicochemical
  • Biological
Cell Lines

  • Primary
  • Secondary
  • Recombinant

YBL – the ideal go-to partner for end-to-end solutions in IDD

  • Single contracting partner which reduces complexity and overhead for our clients
  • Proprietary healthy donor or diseased patient iPSC-derived 2D models, Spheroids & Organoids
  • High Throughput Screening and High Content Imaging capabilities that focus on speed and quality output to reduce turnaround time
  • All round support with upstream & downstream process development along with contract manufacturing services
  • Experienced team of senior scientists as project managers and single point of contact to our partner organizations
  • Dedicated support and guidance to client partners for overall project strategy
  • Driving innovation and securing IP
Check out our list of products & services that can support your disease modeling projects: