Name Human Epididymis Protein 4 (HE4)
What is HE4 HE4 is also known as WAP four-disulfide core domain protein 2 and is encoded by the WFDC2 gene and functions as a protease inhibitor.
What is it used for HE4 is an ovarian cancer biomarker that works both alone and in combination with CA-125 as a diagnostic marker for ovarian cancer.
Source Human Cancer Fluids
Purity High pure (SDS-PAGE and Activity/TP ratio)
Testing method CLIA
Stability 2 years (Real time)
Storage – 70°C
Molecular weight ~25 KDa
Viral testing Negative for HBs-Ag, Anti-HCV and Anti-HIV I & II using CLIA (US-FDA approved) and for absence of viral DNA/RNA for HBV, HIV and HCV using PCR.

YBL Native HE4 salient features

  • Purity: >90% purity for HE4 (high pure) was observed and purity profile was checked using SDS-PAGE and Activity/TP ratio
  • Stability data: HE4 is stable for 3 years at 2-8°C based on real time stability study.
  • Testing Method: ECLIA
  • Testing Platform: Roche-cobas
  • Viral testing: The viral marker test for HBs-Ag, Anti-HCV and Anti-HIV (I and II) was done using CLIA (US-FDA Approved). The antigen was also tested for the absence of viral DNA/RNA for HBV, HIV (I) and HCV using PCR technology.

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