| Name | Hepatitis B surface Antigen (HBsAg-Ay) |
|---|---|
| What is HBsAg-Ay | HBsAg is the serologic hallmark of Hepatitis B Virus (HBV) infection that appears after acute inflammation. It has two determinants; Ad and Ay and two subtype determinants; w and r, and are classified into four major subtypes: adw, adr, ayw and ayr. Having chronic hepatitis B increases the risk of developing liver failure, liver cancer or cirrhosis. At YBL formulation of HBsAg-Ay (high pure) is performed with and without sucrose. |
| What is it used for | It is used in detection of Hepatitis infection or any other liver ailments |
| Source | Human Blood |
| Purity | High pure (SDS-PAGE and Activity/TP ratio) |
| Testing method | ELISA |
| Stability | 4 years (Real time) |
| Storage | 2-8 °C |
| Molecular weight | ~24 KDa |
| Viral testing | Negative for Anti-HCV and Anti-HIV I & II using CLIA (US-FDA approved) and for absence of viral DNA/RNA for HIV and HCV using PCR. |
YBL Native HBsAg-Ay salient features
- Purity percentage: >99% purity for HBsAg-Ay (high pure) was observed and purity profile was checked using SDS-PAGE and Activity/TP ratio.
- Stability data: HBsAg-Ay is stable for 3 years at 2-8°C based on the real time stability study.
- Testing Method: ECLIA
- Testing Platform: BIO-RAD
- Viral testing: The viral marker test for Anti-HCV and Anti-HIV (I and II) was done using CLIA (US-FDA Approved). The antigen was also tested for the absence of viral DNA/RNA for HIV (I) and HCV using PCR technology.
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