Name AlpProstate-Specific Antigen-α1-Anti-Chymotrypsin Complex (PSA- ACT Complex)
What is Prostate-Specific Antigen-α1-Anti-Chymotrypsin complex? PSA is a glycoprotein enzyme encoded in humans by the KLK3 gene and is secreted by the epithelial cells of the prostate gland. PSA exists in two major forms; free PSA and PSA-ACT (PSA bound to Alpha-1 Antichymotrypsin). PSA forms a covalent complex with ACT in human blood.
What is it used for? PSA-ACT Complex is used as a prostrate tumour marker.
Source Human Seminal and Blood Plasma
Purity Part pure (SDS-PAGE and Activity/TP ratio)
Testing method CLIA
Stability 3 years (Real time)
Storage – 20°C
Molecular weight PSA: ~27-28 KDa; ACT: ~60-65 KDa; PSA-ACT Complex: ~87-93 KDa
Viral testing Negative for HBs-Ag, Anti-HCV and Anti-HIV I & II using CLIA (US-FDA approved) and for absence of viral DNA/RNA for HBV, HIV and HCV using PCR.

YBL Native PSA-ACT Complex salient features

  • Purity percentage: >40% purity for PSA (part pure) and purity profile was checked using SDS-PAGE and Activity/TP ratio.
  • Stability data: PSA-ACT Complex is stable for 3 years at -20°C based on real time stability study.
  • Testing Method: ECLIA
  • Testing Platform: Roche-cobas
  • Viral testing: The viral marker test for HBs-Ag, Anti-HCV and Anti-HIV (I and II) was done using CLIA (US-FDA Approved). The antigen was also tested for the absence of viral DNA/RNA for HBV, HIV (I) and HCV using PCR technology.

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