Prostate Specific Antigen (PSA)

Source

Human Seminal Plasma

Description

Prostate-specific antigen, or PSA, is a protein produced by normal, as well as malignant, cells of the prostate gland. This enzyme participates in the dissolution of the seminal fluid coagulum and plays an important role in fertility.
Prostate-specific antigen (PSA), also called as gamma-seminoprotein or kallikrein-3 (KLK3), P-30 antigen, is basically a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland.
PSA is produced for the ejaculate, where it liquefies semen in the seminal       coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.
PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders.

Purity Analysis

≥ 96% by SDS-PAGE

Presentation

Liquid in 0.1M Tris Acetate buffer, pH 6.0 + 0.2 containing 0.09 % w/v Sodium Azide and 20% Glycerol.

Storage

20°C in working aliquots

Stability

2 years at -20°C

Viral testing

The viral marker test negative for HBs-Ag, Anti-HCV, Anti-HIV (I and II) using CLIA (US-FDA approved). The antigen is also tested for the absence of viral DNA/RNA for HBV, HIV (I) and HCV using PCR technology

Material safety note

This product is not for human/animal consumption. Use only in in vitro research or products. All bio-safety precautions must be practiced while handling. Discard (if needed) as per local environmental regulation.