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ExFollicle™
Ex-Vivo Human Hair Follicle Assay
Human Ex-Vivo Hair Follicle Model for Screening Hair Growth Efficacy Formulations
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Test hair growth on Indian donor-derived human hair follicles
ExFollicle™ is an ex vivo human hair follicle assay service designed to evaluate the efficacy of hair-growth and anti-hair-loss test substances on viable hair follicles. All tissue samples are IRB-approved and obtained with informed consent from healthy Indian male donors aged 25 to 40.
Hair follicles from Indian donors, tested for Indian consumers
- Indian Male donors, 25-40 years old
- Informed Consent taken from all donors
- Tissue Collection runs under Institutional Ethics Committee approval
Study Readouts
Follicle size
Length measured by stereo microscopy at QC and at each study time point, compared with untreated follicles
Cellular Architecture and Growth Phase
H&E staining on in-house paraffin sections showing cellular arrangement and growth phase of the cells
Functional markers and Melanin content
Immunofluorescent staining and high-content imaging for TYRP1 and Melan-A showing melanocytes and pigment activity.
Fontana-Masson staining for melanin content indication
Frequently-Asked Questions
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How long can hair follicles stay in culture?
Upto 9 days i.e. the longest study window available.
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How many molecules fit in one study?
Four to Five, each in triplicate per timepoint.
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What controls are used in the study?
Untreated hair follicles, run with the same number of replicates as each treatment group. A vehicle control can be added as an option.
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How long does a study take?
About 3-4 weeks for a typical study, counted from the day the follicles are collected.
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What should I send for the study?
Bring us isolated molecules or formulation. Come with what you have, and we discuss the dose and study plan together before the study starts.
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Can you study cell proliferation or cell death?
Yes. Staining can be tuned for these readouts within your study.
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Which hair follicles do you culture?
Whole hair follicles from male donors around 25-40 years age range. Each hair follicle passes a quality check before study initiation.
Talk to our team
Tell us what you want to test and the claim you need to support. We reply with a feasibility check and a quote.
