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Downstream NAM
Assay Services
In-House Assay Service Portfolio
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Built on the cells we generate in-house — three assay service domains, all conducted under the same quality system, by the same scientific team.
Liver Toxicity Assays
Human-relevant · Context of Use: Mechanistic DILI screening and compound prioritisation in early drug development, pre-IND.
Our liver toxicity services are human-relevant: conducted using human cell-based systems covering the major mechanistic domains of drug-induced liver injury. They are positioned as early-stage decision-support tools — designed to identify hepatotoxic liability and inform go/no-go decisions before committing to costlier in vivo studies, not as regulatory submission-grade data packages. Assays use human cell inputs generated or validated in-house for consistent, traceable results across every study.
GSH/GSSG Ratio Assay
Glutathione Reductase (GR), Peroxidase (GPX), S-transferase (GST) Assays
Reactive Oxygen Species (ROS) Estimation Assay
UDP-Glucuronosyltransferase (UGT) Activity Assay
Malondialdehyde (MDA) Assay
ATP Assay & Mitochondrial Membrane Potential (MMP)
Complex I & II Activity, Fatty Acid Synthase, MTP Pore Assay
CPT1, CD36, Fatty Acid Synthase (FAS) & Uptake Assays
Oil Red O Staining (Lipid Accumulation Assessment)
Drug Discovery Assays
Human-relevant · Context of Use: Hit-to-lead and lead optimisation screening; human-biology-informed compound prioritisation before or in place of in vivo studies.
Our drug discovery assay services use iPSC-derived and primary human cells generated in-house — making them human-relevant by design, with full cell-to-result traceability. They are positioned as fit-for-purpose screening tools for early programme decisions: identifying active compounds, understanding mechanism of action, and flagging liability signals in a human biological context. They are not regulatory submission-grade safety studies — they are the intelligent filter before you get there.
MTT, Calcein AM/Ethidium Homodimer (ATP-based) Cell Viability Assay
LDH Release Assay, Annexin V/PI Apoptosis Profiling
Caspase 3/7 Activity Assay, TUNEL Assay
BrdU & Ki-67 Immunostaining (Proliferation Index)
Total ROS Estimation, DCFH-DA, TBARS (Lipid Peroxidation) Assays
Cell Migration / Invasion Assay, Wound Healing (Scratch) Assay
Angiogenesis (Tube Formation), Anti-Adipogenesis, Autophagy Assays
GLP-1 Peptide Assay, Insulin Release Assay, Nitric Oxide Release Assay
Kinase / Phosphorylation Assays (Western Blot, ELISA)
Inflammation Profiling (Cytokine ELISA, NF-kB, 3D Culture Phenotyping)
Cardiomyocyte-Based Disease Modelling (e.g. Cardiotoxicity, Hypertrophy)
Mitochondrial Density Assessment, Mito Metabolomics Estimation
Personal Care Assay Services
Human-relevant · Context of Use: Ingredient claim substantiation, safety screening, and regulatory dossier support — without animal testing.
Our personal care assay services use primary human keratinocytes, melanocytes, and fibroblasts isolated and characterised in-house to validated purity thresholds — making every endpoint genuinely human-relevant. These services are designed for cosmetic and personal care R&D teams who need credible, cell-based human biology data to support ingredient claims and demonstrate safety to regulators. The assays cover the full range of skin biology endpoints relevant to modern personal care science.
Melanin Content Assay (Intra- & Extracellular)
Tyrosinase Activity Inhibition Assay
Melanogenesis Profiling
Collagen Synthesis Assay (ELISA)
Hyaluronic Acid Secretion Assay
Elastase & Collagenase Inhibition Assays
Elastase & Collagenase Inhibition Assays
FRAP, ORAC, ABTS, DPPH Antioxidant Capacity Assays
ROS Inhibition (DCFDA), SOD & Catalase Activity Assays
Wound Healing / Scratch Assay (Keratinocytes & Fibroblasts)
Neuroinflammation Assay (IL-6, TNF-α Release)
Western Blotting, Protein Extraction & Estimation
Enzyme Inhibition Activity Assays
