Cancer antigen 15-3 (CA 15-3)

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Cancer antigen 15-3 (CA 15-3)

CA 15-3 is derived from the MUC1 gene and overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers. CA 15-3 is used as an important marker for cancer detection particularly breast cancer

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Purity

>95%

Format

Liquid

Source

Human Fluids

Application

Feasible for controls and calibrators in immunoassays

Purity Analysis

Part pure; Low cross contamination for CA 125, CA 19-9, CA 72-4, CEA, AFP and Ferritin is observed and cross contaminants are reported as activity of cross contaminants/activity of CA 15-3 in U/ml. The passing criteria is < 25%, however, YBL tries to restrict the levels to < 10 % for cross contamination

Immunological Activity

Immunoactivity is checked by ECLIA (Roche-Cobas)

Presentation

Liquid in 50mM Phosphate buffer & 150mM Sodium Chloride pH 7.2 -7.6 containing 0.09 % Sodium-Azide

Donor Status

Healthy/Diseased

Storage

2-8°C in working aliquots

Other Information

CA 15-3 part pure is stable for 3 years at 2-8°C

Viral Testing

The viral marker test negative for HBs-Ag, Anti-HCV, Anti-HIV (I and II) using CLIA (US-FDA approved). The antigen is also tested for the absence of viral DNA/RNA for HBV, HIV (I) and HCV using PCR technology

Material Safety Note

This product is not for human/animal consumption. Use only in in vitro research or products. All bio-safety precautions must be practiced while handling. Discard (if needed) as per local environmental regulation

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