PSA-ACT Complex
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PSA-ACT Complex
Prostate Specific Antigen (PSA) is a glycoprotein enzyme, which is encoded in humans by the KLK3 gene and is secreted by the epithelial cells of the prostate gland. PSA exists in two major forms; free PSA and PSA-ACT (PSA bound to Alpha-1 Antichymotrypsin). PSA forms a covalent complex with ACT in human blood and forms a complex known as PSA-ACT Complex, which is used as a prostate tumor marker
Host Species
Mouse
Target Species
Human
Purity
>95%
Format
Liquid
Source
Human Seminal and Blood Plasma
Application
Feasible for controls and calibrators in immunoassays
Purity Analysis
> 40 % part pure by SDS-PAGE
Immunological Activity
Immunoactivity is checked by ECLIA (Roche Cobas)
Presentation
Liquid in 50mM Sodium Acetate buffer, 150mM Sodium Chloride, pH 5.6 + 0.2 containing 0.09 % w/v Sodium Azide, 20% Glycerol and 0.3% Proclin – 300
Donor Status
Healthy/Diseased
Storage
-20°C in working aliquots
Other Information
PSA-ACT Complex is stable for 2 years at -20°C
Viral Testing
The viral marker test negative for HBs-Ag, Anti-HCV, Anti-HIV (I and II) using CLIA (US-FDA approved). The antigen is also tested for the absence of viral DNA/RNA for HBV, HIV (I) and HCV using PCR technology
Material Safety Note
This product is not for human/animal consumption. Use only in in vitro research or products. All bio-safety precautions must be practiced while handling. Discard (if needed) as per local environmental regulation
