β2 Microglobulin (B2M)
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β2 Microglobulin (B2M)
β2 Microglobulin (B2M) protein is encoded by the B2M gene and is a component of MHC class I molecules, which are present on all nucleated cells (excluding red blood cells). Low levels of B2M serve as a marker against liver or kidney disease whereas high levels indicate infection and inflammation
Host Species
Mouse
Target Species
Human
Purity
>95%
Format
Liquid
Source
Human Urine
Application
Feasible for controls and calibrators in immunoassays
Purity Analysis
> 98% high pure and > 70% part pure by SDS-PAGE
Immunological Activity
Immunoactivity is confirmed by Latex Turbidimetry (Turbilatex, Spinreact)
Presentation
Liquid High pure in 40mM Phosphate buffer, 150mM Sodium Chloride, 1mM EDTA Sodium Salt, pH 7.2 + 0.2 containing 0.05 % w/v Sodium Azide and Part pure in 50mM Phosphate buffer, 150mM Sodium Chloride, pH 7.2 + 0.2 containing 0.09 % w/v Sodium Azide
Donor Status
Healthy/Diseased
Storage
2-8°C in working aliquots
Other Information
B2M is stable for 2 years at 2-8°C
Viral Testing
The viral marker test negative for HBs-Ag, Anti-HCV, Anti-HIV (I and II) using CLIA (US-FDA approved). The antigen is also tested for the absence of viral DNA/RNA for HBV, HIV (I) and HCV using PCR technology
Material Safety Note
This product is not for human/animal consumption. Use only in in vitro research or products. All bio-safety precautions must be practiced while handling. Discard (if needed) as per local environmental regulation
